Women play a vital role in the advancement of global health, yet men still remain the majority holders of leadership positions. Leadership is key for improving performance, strengthening workforce capacity, enhancing connection enhancing connections with target populations, and increasing the ability to respond effectively to change and thus key to achieving sustainable development goals (SDGs) targets. The Women Leaders in Global Health Initiative, a joint initiative of Women in Global Health and the Global Health Council, envisions a world where women are represented in equal numbers to men at the highest levels of decision making and visibility. The initiative strives to address the individual, institutional and political challenges that impede women’s positioning as leaders in global health through strategic advocacy, networking, mentorship and capacity building.