Founded in 1967, the Institut de recherches cliniques de Montréal was the first research centre in Québec to bring together fundamental science researchers and clinicians under one roof. Based on this model, which was unique at the time, the IRCM has grown to become one of Canada’s leading research centres, with 35 research units organized into five research divisions. The IRCM is an independent non-profit research institution affiliated with the Université de Montréal, and with a long-standing association with McGill University. The IRCM Clinic is also affiliated with the Centre hospitalier de l’Université de Montréal (CHUM). All IRCM researchers hold appointments as university research professors at the Université de Montréal, and most laboratory directors are associated to various departments at McGill.